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How to use medicine reasonably

Date:2020-03-03

Because the condition and pathogen of human are changeable, it is difficult to achieve absolute rational drug use. Generally speaking, rational drug use is relative, which includes four basic elements: safety, effectiveness, economy and Appropriateness.


First of all, safety is emphasized in drug use. Only under this premise can rational drug use be discussed. The significance of safety is to maximize the treatment effect with the least treatment risk.


Secondly, the effectiveness of drugs, which is the key to the use of drugs. If there is no curative effect, it will lose the significance of the drug itself. There are great differences in the effectiveness of different drugs in clinical: eradicating the source of disease, curing the disease, delaying the process of disease, alleviating clinical symptoms, preventing the occurrence of disease, avoiding adverse reactions, regulating the physiological function of human body and so on.


In the process of safe and effective drug use, we should also consider whether it is economic and affordable for patients. If a drug is safe and effective but expensive, it can't be used by patients, and it's not reasonable.


Finally, it is appropriate to include seven aspects:


1. Appropriate drugs. According to the patient's physical condition, in the same kind of drugs, select the most appropriate drugs, in the case of the need for a combination of multiple drugs, we must also pay attention to the appropriate combination of drugs.


2. Appropriate dose. Strictly follow the dosage prescribed by the doctor's order or instructions, and do not increase or decrease the dosage at will according to your own feelings.


3. Appropriate time. According to the law of drug action in vivo, the time and interval of drug administration were designed. The most reasonable administration plan is to design appropriate dosage and interval time. Some drugs need to be taken before meals, some after meals, and some between meals. If you don't follow the way of taking it, taking it at will will affect the effect or cause irritation to the stomach.


4. Appropriate ways. It refers to the comprehensive consideration of the purpose of the drug, the nature of the drug, the patient's physical condition, safety, economy, simplicity and other factors. Patients are suitable for oral medication, try not to use intravenous medication. Now we advocate a kind of sequential therapy, that is, after the infusion to control the symptoms, change the oral medicine for consolidation treatment.


5. Appropriate patients. The same disease occurs in two people. Due to the differences between individuals, even if the same drug is applied, a comprehensive trade-off should be carried out. A treatment plan cannot be applied to all people.


6. Proper course of treatment. Prolonging the administration time, it is easy to produce accumulation poisoning, bacterial resistance, drug dependence and other adverse reactions, and when the symptoms are controlled, the drug will be stopped, often unable to completely cure the disease. Only by grasping the cycle, can we get twice the result with half the effort. If we want to fight for a long time in the treatment of tuberculosis, we need to take medicine for at least half a year, while in the treatment of dysentery, we need to make a quick decision, generally using 3-5 days of treatment time.


7. Appropriate treatment objectives. Patients often want to get rid of the disease completely, or unrealistically require the use of drugs without side effects. Doctors and patients should adopt a positive, correct and objective attitude to reach a consensus according to the specific situation.

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